7-表-10-脫乙酰基紫杉醇用途
10-Deacetyltaxol (10-Deacetylpaclitaxel) 是從紅豆杉中分離得到的一種紫杉醇衍生物。10-Deacetyltaxol (10-Deacetylpaclitaxel) 能促進微管蛋白的聚合，在體外抑制由冷或鈣離子誘導的微管解聚。10-Deacetyltaxol (10-Deacetylpaclitaxel) 對人腦膠質細胞瘤和神經母細胞瘤細胞具有細胞毒性。
1、產品物理參數：
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常用名
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7-表-10-脫乙?；仙即?/span>
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英文名
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Deacetyltaxol
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CAS號
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78432-77-6
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分子量
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811.870
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密度
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1.4±0.1 g/cm3
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沸點
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959.5±65.0 °C at 760 mmHg
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分子式
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C45H49NO13
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熔點
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182-184oC
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閃點
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534.1±34.3 °C
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2、7-表-10-脫乙?；仙即嘉锢砘瘜W性質
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密度
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1.4±0.1 g/cm3
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沸點
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959.5±65.0 °C at 760 mmHg
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熔點
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182-184oC
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分子式
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C45H49NO13
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分子量
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811.870
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閃點
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534.1±34.3 °C
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精*確質量
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811.320374
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PSA
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215.22000
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LogP
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6.74
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蒸汽壓
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0.0±0.3 mmHg at 25°C
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折射率
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1.652
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儲存條件
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-20°C Freezer
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3、7-表-10-脫乙?；仙即加⑽膭e名
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benzenepropanoic acid, β-(benzoylamino)-α-hydroxy-, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, (αR,βS)-
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7-epi-10-deacetyltaxol
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b-(Benzoylamino)-a-hydroxy-benzenepropanoic acid [2aR-[2aa,4b,4ab,6b,9a(aR*,bS*),11a,12a,12aa,12ba]]-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester
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(2α,5β,7β,10β,13α)-4-(acetyloxy)-13-{[(2R,3S)-3-(benzoylamino)-2-hydroxy-3-phenylpropanoyl]oxy}-1,7,10-trihydroxy-9-oxo-5,20-epoxytax-11-en-2-yl benzoate
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7-EPI-10-DEACETYL PACLITAXEL
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10-DEACETYLTAXOL
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10-Desacetyl Paclitaxel
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(2α,5β,7β,10β,13α)-4-Acetoxy-13-{[(2R,3S)-3-(benzoylamino)-2-hydroxy-3-phenylpropanoyl]oxy}-1,7,10-trihydroxy-9-oxo-5,20-epoxytax-11-en-2-yl benzoate
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10-Desacetyltaxol
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Benzenepropanoic acid, β-(benzoylamino)-α-hydroxy-, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,6,11-trihydroxy-4a,8,13,1 3-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, (αR,βS)-
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10-Deacetylpaclitaxel
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10-DAT
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